β-Carotene from rice for human nutrition?

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β-Carotene in Golden Rice is as good as β-carotene in oil at providing vitamin A to children.

BACKGROUND Golden Rice (GR) has been genetically engineered to be rich in β-carotene for use as a source of vitamin A. OBJECTIVE The objective was to compare the vitamin A value of β-carotene in GR and in spinach with that of pure β-carotene in oil when consumed by children. DESIGN Children (n = 68; age 6-8 y) were randomly assigned to consume GR or spinach (both grown in a nutrient solutio...

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Genetic Stability Developed for β-Carotene Synthesis in BR29 Rice Line Using Dihaploid Homozygosity

Obtaining transgenic crop lines with stable levels of carotenoids is highly desirable. We addressed this issue by employing the anther culture technique to develop dihaploid lines containing genes involved in β-carotene metabolism. First, we used Agrobacterium- mediated transformation to develop primary transgenic plants containing the β-carotene biosynthetic genes, phytoene synthase (psy) and ...

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Golden Rice and 'Golden' crops for human nutrition.

Micronutrients are essential for a healthy life. Humans do not produce micronutrients, and hence they must obtain them through the foodchain. Staple crops are the predominant food source of mankind, but need to be complemented by other foodstuffs because they are generally deficient in one or the other micronutrient. Breeding for micronutrient-dense crops is not always a viable option because o...

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β-Carotene and other carotenoids in protection from sunlight.

Protection against skin damage from sunlight by nutritional means has been examined. Likewise, there has been work on the topical application of phytochemicals to the skin. This review focuses on the nutritional aspect of phytochemicals in humans-ie, the provision of carotenoid micronutrients by dietary means to the skin and their role in protection. Human intervention studies have documented p...

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Characterization of human β,β-carotene-15,15'-monooxygenase (BCMO1) as a soluble monomeric enzyme.

The formal first step in in vitamin A metabolism is the conversion of its natural precursor β,β-carotene (C40) to retinaldehyde (C20). This reaction is catalyzed by the enzyme β,β-carotene-15,15'-monooxygenase (BCMO1). BCMO1 has been cloned from several vertebrate species, including humans. However, knowledge about this protein's enzymatic and structural properties is scant. Here we expressed h...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 2009

ISSN: 0002-9165,1938-3207

DOI: 10.3945/ajcn.2009.28142